ANSWERS TO MUTATION QUESTIONS FROM REVIEW SHEET

2. Make a complementary strand of mRNA below this strand of DNA

TACGGGTCTAAGTGGACACCCATC

AUGCCCAGAUUCACCUGUGGGUAG = mRNA

AUG/CCC/AGA/UUC/ACC/UGU/GGG/UAG

3. What kind of mutation?

DNA = TACGGGTCTAGAGTGGACACCCATC

Red G has been added so it is a frameshift mutation, specifically an insertion mutation.

4. What kind of mutation?

DNA = TACGGGTCTCAGTGGACACCCATC

Red C was a G in original DNA

mRNA from this DNA is in red below

mRNA from original DNA in blue

AUG/CCC/AGA/GUC/ACC/UGU/GGG/UAG

AUG/CCC/AGA/UUC/ACC/UGU/GGG/UAG

They are alike except for the fourth codon

GUC = valine

UUC = phenylalanine

So this is a point or base substitution mutation, specifically a missense mutation